Before starting Semaglutide + B12, your medical prescriber will review your health history, current medications, previous weight-management treatments, and treatment goals to determine the most appropriate starting dose and plan for you. Be sure to discuss any history of pancreatitis, gallbladder problems, significant digestive conditions, kidney concerns, diabetes-related complications, or thyroid cancer, including a personal or family history of medullary thyroid carcinoma or MEN2. Let your provider know if you are pregnant, breastfeeding, planning pregnancy, or taking other medications that affect blood sugar or appetite. Your dose may be adjusted gradually based on tolerance, response, and progress, with the goal of finding the lowest effective dose that supports your weight-management plan comfortably. Prescription required.