Progesterone is a naturally occurring steroid hormone produced primarily in the ovaries following ovulation, and in smaller amounts by the adrenal glands. It plays a central role in regulating the menstrual cycle, preparing the uterine lining, and maintaining hormone balance alongside estrogen. In clinical hormone care, progesterone therapy may be included in an individualized treatment plan when a licensed provider determines it is clinically appropriate following a review of health history, symptoms, and current medications.

• Women's health and hormone optimization protocols
• Menopause and perimenopause care plans
• Fertility-adjacent endocrinology practices
• Compounding pharmacies (US-formulated)

Micronized oral progesterone — the bioidentical form — is structurally identical to the hormone produced naturally in the body, distinguishing it from synthetic progestins. Available in 100 mg and 150 mg capsules for precise dose titration. Typically taken at night due to its mild sedative quality. Formulation and dosing are determined by the provider based on individual labs, symptoms, and hormone care goals. All use requires a valid prescription and ongoing provider oversight.