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Glutathione is the body's most abundant endogenous antioxidant — a tripeptide synthesized naturally in virtually every cell, with the highest concentrations found in the liver. It plays a central role in neutralizing free radicals, supporting immune function, detoxification pathways, and maintaining cellular redox balance. Levels naturally decline with age, chronic stress, and certain health conditions. In a clinician-directed wellness setting, glutathione may be included in an individualized care plan when a provider determines it is appropriate following a review of health history, current medications, and treatment goals.
Unique among antioxidants for being synthesized endogenously from three amino acids — glutamate, cysteine, and glycine — rather than obtained solely from diet. Injectable glutathione delivers concentrations that bypass the limited oral bioavailability of glutathione supplements, as the tripeptide is largely broken down in the gastrointestinal tract before absorption. Often administered alongside Vitamin C in IV wellness protocols to enhance and regenerate antioxidant activity. Formulation, dose, and frequency are determined by the provider based on individual health history and wellness objectives.